A study on risk factor, etiology and outcomes of acute pancreatitis

Rumana Khanam; Sahithya Gajjala; Sai Chandana Musangi; Jayanthi  Errolla; Hareesh Kattambai; Tanvi Shazia; Firdouse  Amena

doi:10.38022/ajhp.v5i3.108

Rumana Khanam Assistant Professor, Department of Pharmacy Practice, Smt. Sarojini Ramulamma College of Pharmacy, (Palamuru University), Seshadri Nagar, Mahabubnagar District, Telangana State, India.
rumanakhan98765@gmail.com
Gajjala Sahithya Pharm. D V year, Smt. Sarojini Ramulamma College of Pharmacy, (Palamuru University), Seshadri Nagar, Mahabubnagar District, Telangana State, India.
Musangi Sai Chandana Pharm. D V year, Smt. Sarojini Ramulamma College of Pharmacy, (Palamuru University), Seshadri Nagar, Mahabubnagar District, Telangana State, India.
Errolla Jayanthi Pharm. D V year, Smt. Sarojini Ramulamma College of Pharmacy, (Palamuru University), Seshadri Nagar, Mahabubnagar District, Telangana State, India.
Kattambai Hareesh Pharm. D V year, Smt. Sarojini Ramulamma College of Pharmacy, (Palamuru University), Seshadri Nagar, Mahabubnagar District, Telangana State, India.
Shazia Tanvi Pharm. D V year, Smt. Sarojini Ramulamma College of Pharmacy, (Palamuru University), Seshadri Nagar, Mahabubnagar District, Telangana State, India.
Amena Firdouse Pharm. D V year, Smt. Sarojini Ramulamma College of Pharmacy, (Palamuru University), Seshadri Nagar, Mahabubnagar District, Telangana State, India.

DOI https://doi.org/10.38022/ajhp.v5i3.108

Abstract

A prospective observational study was conducted on 80 patients with acute pancreatitis to assess clinical presentation, management, and outcomes. Abdominal pain (93.75%) was the most common symptom, followed by vomiting (37.5%) and constipation (10%). All patients received supportive treatment with intravenous fluids, and most required analgesics (97.5%), nutritional support (56.25%), antibiotics (25%), or insulin therapy (12.5%). Interventional procedures such as ERCP or drainage were performed in 6.25% of cases. Symptomatic relief was achieved in the majority, with 95% experiencing pain resolution. Complications included transient hyperglycemia (12.5%), pseudocyst formation (3.75%), and infected necrosis (2.5%). The average hospital stay ranged from 7 to 10 days in uncomplicated cases, with 18.8% experiencing prolonged admission. Overall survival was 97.5%, with mortality occurring in 2 patients due to severe necrotising pancreatitis. The study highlights that timely fluid resuscitation, effective pain management, and appropriate nutritional and interventional support are essential for favourable outcomes in acute pancreatitis.

Keywords: Acute pancreatitis, Gastrointestinal emergency, Clinical manifestations, Supportive therapy, Pancreatic pseudocyst, Necrotizing pancreatitis

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