Various types of drug treatment for covid19 pandemic disease

Abstract

The leading theme of the article is the naming of newly discovered coronavirus drugs, for the 2019 virus, Severe acute respiratory syndrome coronavirus(SARS-Cov-2).SARS-Cov-2 is the 3rd zoonotic coronavirus after SARS-Cov and MERS-Cov. The first human coronavirus (HCoV) appeared in reports in the mid-1960s and was isolated from persons with the common cold. Two species were first detected: HCoV-229E and subsequently, then, more species were discovered. Human coronavirus 229E (HCoV-229E) is one of the first coronavirus strains being identified in Wuhan, which is creating a hectic boom globally.. Coronavirus disease was first discovered in humans in the 1930s. The virus, human coronavirus 229E was first isolated in 1965. (HCOV-229E). A new corona virus was identified in 2012 with a SARS-like illness, called middle east respiratory syndrome ( MERS) COV resulted in a limited number of outbreaks, mostly in Saudi Arabia. In December 2019, a novel coronavirus (nCOV) was identified in Wuhan, China, which was isolated on 7 January 2020. Current clinical management includes infection prevention and control measures and supportive care including supplemental oxygen and mechanical ventilatory support. Currently, Antiviral agents Remdesivir, Hydrochloroquine, Chloroquine, Lopinavir, Umifenovir, Favipiravir, Oseltavir, and supporting agents like Ascorbic acid, Azithromycin, Corticosteroids, Nitric oxide, IL-6 Antagonist are using against virus. Evolving research and clinical data regarding the virologic SARS-CoV-2 suggest a potential list of repurposed drugs with appropriate pharmacological effects and therapeutic efficacies in treating COVID-19 patients. In this review, we will update and summarize the most common and plausible drugs for the treatment of COVID-19 patients. We hope that this review will provide useful and most updated therapeutic drugs to prevent, control, and treat COVID-19 patients until the approval of vaccines and specific drugs targeting SARS-CoV-2.